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HIV symptoms

the First Stage

HIV infection comes in three stages. The first stage is called acute infection or seroconversion, and it typically happens within two to six weeks after exposure or becoming infected. This is when the body's immune system puts up a fight against HIV. The symptoms of acute infection look similar to those of other viral illnesses and are often compared to those of the flu. The symptoms may last a week or two and then completely go away as the virus goes into a non-symptomatic stage.

The initial symptoms of acute HIV infection may include:

• Headache
• Diarrhea
• Nausea and vomiting
• Fatigue
• Aching muscles
• Sore throat
• Red rash that doesn't itch, usually on the torso.
• Fever

Call Your Doctor !!!!

 

You think you have come in contact with HIV. Doctors can now prevent HIV from taking hold in the body if they act quickly after initial infection. Health care workers, police, and firefighters who are exposed to HIV-infected blood often use a process that involves taking anti-HIV drugs to protect themselves. These drugs must be taken within hours or days of initial exposure.

You may be tested for HIV using highly sensitive tests that detect both HIV antigen, a protein produced by the virus immediately after infection, and HIV antibodies. This test can confirm a diagnosis within days of infection. (Regular HIV tests don't work this soon after infection; they can only detect antibodies.) You may be given anti-HIV drugs to take for a prescribed period of time. There may be unpleasant side effects to these drugs, but they may stop HIV from infecting you.

Most people don't know they've been infected with HIV, but weeks later they may experience the symptoms of seroconversion. These symptoms mean the body is trying to fight HIV.

 

 the Second Stage

After the first seroconversion period, the immune system loses the battle with HIV and symptoms go away. HIV infection goes into its second stage, which can be a long period without symptoms, called the asymptomatic period. This is when people may not know they are infected and can pass HIV on to others. This period can last 10 or more years.

 

During this period without symptoms, HIV is slowly killing the CD4 T-cells and destroying the immune system. Blood tests during this time can reveal the number of these CD4 T-cells. Normally, a person has a CD4 T-cell count between 450 and 1,400 cells per microliter. This number changes constantly, depending on a person's state of health. For an HIV-infected person, the number of CD4 T-cells steadily drops, making them vulnerable to other infections -- and in danger of developing AIDS.

 

AIDS (acquired immune deficiency syndrome) is the advanced stage of HIV infection. When the CD4 T-cell number drops below 200, people are diagnosed with AIDS.

Someone infected with HIV can also be diagnosed with AIDS if they have an “AIDS defining illness” such as Kaposi’s sarcoma (a form of skin cancer) or pneumocystis pneumonia (a lung disease).

Fortunately, combination medications used to treat HIV -- a ''cocktail'' – can help rebuild the immune system. These drugs can be expensive and pose challenges with side effects, but it is critical to not stop taking them without talking to your doctor. It is also important not to take part of the medications without taking the others. People with low CD4 T-cells may also receive drugs to prevent opportunistic infections. These preventative medications should be taken until the CD4 count has improved. 

 

Some people don't know they were infected with HIV, and only discover their HIV infection after experiencing some of these HIV-related symptoms:

• Being tired all of the time
• Swollen lymph nodes in the neck or groin
• Fever lasting for more than 10 days
• Night sweats
• Unexplained weight loss
• Purplish spots on the skin that don't go away
• Shortness of breath
• Severe, long-lasting diarrhea
• Yeast infections in the mouth, throat, or vagina
• Easy bruising or unexplained bleeding

 Research

 
HIV/AIDS research includes all medical research that attempts to prevent, treat, or cure HIV/AIDS, as well as fundamental research about the nature of HIV as an infectious agent and AIDS as the disease caused by HIV.
Currently, no cure for HIV/AIDS exists. The most universally recommended method for the prevention of HIV/AIDS is to avoid blood-to-blood contact between people and to practice safe sex. The most recommended method for treating HIV is to receive attention from a doctor in charge of coordinating the patient's management of HIV/AIDS.

 
Many governments and research institutions participate in HIV/AIDS research. This research includes behavioral health interventions, such as research into sex education, and drug development, such as research into microbicides for sexually transmitted diseases, HIV vaccines, and antiretroviral drugs. Other medical research areas include the topics of pre-exposure prophylaxis, post-exposure prophylaxis, and circumcision and HIV.

 

Reference

1. Israël N, Gougerot-Pocidalo MA (1997). "Oxidative stress in human immunodeficiency virus infection". Cell. Mol. Life Sci. 53 (11-12): 864–70. doi:10.1007/s000180050106. PMID 9447238.
2. Michod RE, Bernstein H, Nedelcu AM (May 2008). "Adaptive value of sex in microbial pathogens". Infect. Genet. Evol. 8 (3): 267–85. doi:10.1016/j.meegid.2008.01.002. PMID 18295550.
3. Hallenberger S, Bosch V, Angliker H, Shaw E, Klenk HD, Garten W; Bosch; Angliker; Shaw; Klenk; Garten (November 26, 1992). "Inhibition of furin-mediated cleavage activation of HIV-1 glycoprotein gp160". Nature 360 (6402): 358–61. Bibcode:1992Natur.360..358H. doi:10.1038/360358a0. PMID 1360148.
4. Gelderblom HR (1997). "Fine structure of HIV and SIV". In Los Alamos National Laboratory. HIV sequence compendium. Los Alamos National Laboratory. pp. 31–44.
5. Robertson DL, Hahn BH, Sharp PM (1995). "Recombination in AIDS viruses". J Mol Evol. 40 (3): 249–59. doi:10.1007/BF00163230. PMID 7723052.
6. Rambaut A, Posada D, Crandall KA, Holmes EC (January 2004). "The causes and consequences of HIV evolution". Nature Reviews Genetics 5 (52–61): 52–61. doi:10.1038/nrg1246. PMID 14708016.
7. Perelson AS, Ribeiro RM (October 2008). "Estimating drug efficacy and viral dynamic parameters: HIV and HCV". Stat Med 27 (23): 4647–57. doi:10.1002/sim.3116. PMID 17960579.
8. Sodora DL, Allan JS, Apetrei C, Brenchley JM, Douek DC, Else JG, Estes JD, Hahn BH, Hirsch VM, Kaur A, Kirchhoff F, Muller-Trutwin M, Pandrea I, Schmitz JE, Silvestri G (2009). "Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts". Nature Medicine 15 (8): 861–865. doi:10.1038/nm.2013. PMC 2782707. PMID 19661993.
9. Holzammer S, Holznagel E, Kaul A, Kurth R, Norley S (2001). "High virus loads in naturally and experimentally SIVagm-infected African green monkeys". Virology 283 (2): 324–31. doi:10.1006/viro.2001.0870. PMID 11336557.
10. Kurth, R. and Norley, S. (1996). "Why don't the natural hosts of SIV develop simian AIDS?". J. NIH Res. 8: 33–37.
11. Baier M, Dittmar MT, Cichutek K, Kurth R; Dittmar; Cichutek; Kurth (1991). "Development of vivo of genetic variability of simian immunodeficiency virus". Proc. Natl. Acad. Sci. U.S.A. 88 (18): 8126–30. Bibcode:1991PNAS...88.8126B. doi:10.1073/pnas.88.18.8126. PMC 52459. PMID 1896460.
12. Daniel MD, King NW, Letvin NL, Hunt RD, Sehgal PK, Desrosiers RC; King; Letvin; Hunt; Sehgal; Desrosiers (1984). "A new type D retrovirus isolated from macaques with an immunodeficiency syndrome". Science 223 (4636): 602–5. Bibcode:1984Sci...223..602D. doi:10.1126/science.6695172. PMID 6695172.
13. Keele BF, Jones JH, Terio KA, Estes JD, Rudicell RS, Wilson ML, Li Y, Learn GH, Beasley TM, Schumacher-Stankey J, Wroblewski E, Mosser A, Raphael J, Kamenya S, Lonsdorf EV, Travis DA, Mlengeya T, Kinsel MJ, Else JG, Silvestri G, Goodall J, Sharp PM, Shaw GM, Pusey AE, Hahn BH (2009). "Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz". Nature 460 (7254): 515–519. Bibcode:2009Natur.460..515K. doi:10.1038/nature08200. PMC 2872475. PMID 19626114.
14. Thomson MM, Pérez-Alvarez L, Nájera R (2002). "Molecular epidemiology of HIV-1 genetic forms and its significance for vaccine development and therapy". Lancet Infectious Diseases 2 (8): 461–471. doi:10.1016/S1473-3099(02)00343-2. PMID 12150845.
15. Carr JK, Foley BT, Leitner T, Salminen M, Korber B, McCutchan F (1998). "Reference sequences representing the principal genetic diversity of HIV-1 in the pandemic" (PDF). In Los Alamos National Laboratory (ed.). HIV sequence compendium. Los Alamos, New Mexico: Los Alamos National Laboratory. pp. 10–19.
16. Osmanov S, Pattou C, Walker N, Schwardländer B, Esparza J (2002). "Estimated global distribution and regional spread of HIV-1 genetic subtypes in the year 2000". Acquired Immune Deficiency Syndrome 29 (2): 184–190. doi:10.1097/00042560-200202010-00013. PMID 11832690.